منابع مشابه
DNA sequencing: bench to bedside and beyondy
Fifteen years elapsed between the discovery of the double helix (1953) and the first DNA sequencing (1968). Modern DNA sequencing began in 1977, with development of the chemical method of Maxam and Gilbert and the dideoxy method of Sanger, Nicklen and Coulson, and with the first complete DNA sequence (phage rX174), which demonstrated that sequence could give profound insights into genetic organ...
متن کاملDNA sequencing: bench to bedside and beyond†
Fifteen years elapsed between the discovery of the double helix (1953) and the first DNA sequencing (1968). Modern DNA sequencing began in 1977, with development of the chemical method of Maxam and Gilbert and the dideoxy method of Sanger, Nicklen and Coulson, and with the first complete DNA sequence (phage X174), which demonstrated that sequence could give profound insights into genetic organi...
متن کاملPersonalized Medicine and Cardiovascular Disease: From Genome to Bedside
Cardiovascular diseases are among the leading causes of morbidity and mortality in the developed world despite advances in cardiac care over the last few decades. Although most of these advances in cardiovascular medicine have been made through trials of therapies on a population scale, the success of such therapies in a patient often is dependent on particular aspects of each individual. In th...
متن کاملWhole Genome Sequencing as a Genetic Test for Autism Spectrum Disorder: From Bench to Bedside and then Back Again.
Autism spectrum disorder (ASD) is characterized by repetitive patterns of behaviour and impairments in social interactions and communication abilities. Although ASD is a heterogeneous disorder, it is a highly genetic condition for which genetic testing is routinely performed. Microarray analysis is currently the standard of care genetic test for ASD, however whole genome sequencing offers sever...
متن کاملFrom bench to bedside
Because the microcirculation has emerged as an important reanimation target, appropriate methods to monitor the microcirculatory function are crucial. Several teams have now succeeded in crossing this bridge from bench to bedside, but the choice of the tissues of interest remains a debate. The potential accessible vascular beds that doctors could use in reanimation strategies and the relationsh...
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ژورنال
عنوان ژورنال: Yearbook of Medical Informatics
سال: 2013
ISSN: 0943-4747,2364-0502
DOI: 10.1055/s-0038-1638852